CD27
This gene encodes a protein that belongs to the TNF-receptor superfamily. The development and ongoing maintenance of T cell immunity depend on this receptor. It controls the activation of B cells and the production of immunoglobulin by binding to the receptor CD70. This receptor transmits the signals that activate MAPK8/JNK and NF-kappaB. It has been demonstrated that the adaptor proteins TRAF2 and TRAF5 mediate this receptor's signaling mechanism. This receptor can bind to the proapoptotic protein CD27-binding protein (SIVA), which is thought to be crucial in the apoptosis this receptor causes.
| Full Name | CD27 molecule |
| Gene ID | Human: 939 Mouse: 21940 Rat: 500318 Monkey: 712693 |
| UniProt ID | Human: P26842 Mouse: P41272 Rat: Q501W2 Monkey: F6RCS3 |
| Alternative Names | CD27; T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; CD27 molecule |
Product List
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Magic™ Human CD24 & CD274 MC-38 Cell Line
[CAT#: S01YF-0324-KX91]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD24 & CD274 Target Family: CD Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD27 HT1080 Cell Line
[CAT#: S01YF-0123-KX349]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD27 Target Family: CD Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HT1080 Assay Types: Drug screening and biological assays
Magic™ Human CD274 & CCL1 MC-38 Cell Line
[CAT#: S01YF-0324-KX87]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & CCL1 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD274 & CD86 CT26 Cell Line
[CAT#: S01YF-0324-KX63]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & CD86 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
Magic™ Human CD274 B16F10-Sirpa-Overexpression Cell Line
[CAT#: S01YF-0324-KX42]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: B16F10-Sirpa-Overexpression Assay Types: Functional assay and biological assay
Magic™ Human CD274 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX137]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human CD274 CT26 Cell Line
[CAT#: S01YF-0123-KX185]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
Magic™ Human CD274 DLD1 Cell Line
[CAT#: S01YF-0123-KX152]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: DLD1 Assay Types: Drug screening and biological assays
Magic™ Human CD274 EMT6 Cell Line
[CAT#: S01YF-0324-KX72]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: EMT6 Assay Types: Functional assay and biological assay
Magic™ Human CD274 H22 Cell Line
[CAT#: S01YF-0324-KX78]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: H22 Assay Types: Functional assay and biological assay
Magic™ Human CD274 H22-KOmPDL1 Cell Line
[CAT#: S01YF-0123-KX150]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: H22-KOmPDL1 Assay Types: Drug screening and biological assays
Magic™ Human CD274 HEK293T Cell Line
[CAT#: S01YF-0123-KX346]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CD274 HEK293T-OS8 Cell Line
[CAT#: S01YF-0123-KX260]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T-OS8 Assay Types: Drug screening and biological assays
Magic™ Human CD274 Hepa1-6 Cell Line
[CAT#: S01YF-0324-KX81]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: Hepa1-6 Assay Types: Functional assay and biological assay
Magic™ Human CD274 Jurkat Cell Line with NFAT-Luc2 Reporter
[CAT#: S01YF-1222-KX896]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Jurkat Assay Types: Drug screening and biological assays
Magic™ Human CD274 LL/2 Cell Line
[CAT#: S01YF-0324-KX85]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: LL/2 Assay Types: Functional assay and biological assay
Magic™ Human CD274 MC-38 Cell Line
[CAT#: S01YF-0123-KX304]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC-38 Assay Types: Drug screening and biological assays
Magic™ Human CD274 MC-38-KOmPDL1 Cell Line
[CAT#: S01YF-0123-KX211]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC-38-KOmPDL1 Assay Types: Drug screening and biological assays
Magic™ Human CD274 MC-38-Sirpa-KO Cell Line
[CAT#: S01YF-0324-KX128]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38-Sirpa-KO Assay Types: Functional assay and biological assay
Magic™ Human CD274 & HVEM B16F10 Cell Line
[CAT#: S01YF-0324-KX38]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & HVEM Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: B16F10 Assay Types: Functional assay and biological assay
Magic™ Human CD274 & HVEM CT26 Cell Line
[CAT#: S01YF-0324-KX58]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & HVEM Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
Magic™ Human CD274 & NT5E CT26 Cell Line
[CAT#: S01YF-0123-KX37]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & NT5E Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
Magic™ Human CD274 & NT5E MC-38 Cell Line
[CAT#: S01YF-0123-KX36]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & NT5E Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC-38 Assay Types: Drug screening and biological assays
Magic™ Human CD274 & PVR CT26 Cell Line
[CAT#: S01YF-0123-KX16]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & PVR Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
Magic™ Human CD274 4T1 Cell Line
[CAT#: S01YF-0324-KX27]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: 4T1 Assay Types: Functional assay and biological assay
Magic™ Human CD274 B16F10 Cell Line
[CAT#: S01YF-0324-KX40]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: B16F10 Assay Types: Functional assay and biological assay
Magic™ Human CD274 B16F10-Sirpa-KO Cell Line
[CAT#: S01YF-0324-KX41]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: B16F10-Sirpa-KO Assay Types: Functional assay and biological assay
Magic™ Cyno CD274 HEK293T Cell Line
[CAT#: S01YF-0123-KX294]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 Target Family: Immune Checkpoint Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Cynomolgus PD-L1 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX164]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-L1 Target Family: Immune Checkpoint Target Protein Species: Cynomolgus Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Human B7-H3 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX133]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: B7-H3 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
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