Human CD27 Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX360]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human CD27 for Protein Expression.
Target Protein
CD27
Target Protein Species
Human
Target Classification
CD
Target Research Area
Cancer Research; Immunology Research
Related Diseases
Lymphoproliferative Syndrome; Combined Immunodeficiency
Target Family
CD
Vector
pME
Vector Type
Mammalian Transient Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
CMV, SV40, EF1a, CAG etc.
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
Protein Expression
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
CD27 molecule
Introduction
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Alternative Names
CD27; T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; CD27 molecule
Gene ID
UniProt ID
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