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CCR1

The beta chemokine receptor protein that this gene produces is projected to be a seven transmembrane protein, much like G protein-coupled receptors. The ligands for this receptor are monocyte chemoattractant protein 3 (MCP-3), RANTES, regulated on activation normal T expressed and secreted protein (MIP-1 alpha), and myeloid progenitor inhibitory factor-1 (MPIF-1). The signaling pathway regulated by chemokines and their receptors is essential for attracting effector immune cells to the site of inflammation. CCR5 Pathway in Macrophages and Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions are two of its associated pathways. This gene's Gene Ontology (GO) annotations include chemokine receptor activity and G protein-coupled receptor activity.

Full Name C-C motif chemokine receptor 1
Gene ID Human: 1230
Mouse: 12768
Rat: 57301
Monkey: 574188
UniProt ID Human: P32246
Mouse: P51675
Rat: Q9JLY8
Monkey: P56482
Alternative Names CKR1; CD191; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1; C-C CKR-1; CC-CKR-1; CCR-1; LD78 receptor; MIP-1alpha-R; RANTES receptor; RANTES-R; chemokine (C-C motif) receptor 1; macrophage inflammatory protein 1-alpha receptor; CCR1; C-C motif chemokine receptor 1

Product List

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Product Category:
Membranes
Target Protein: CCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membranes
Target Protein: CCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Product Category:
Membranes
Target Protein: CCR1 Target Family: Chemokine Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Internalization assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Internalization assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
Product Category:
Membranes
Target Protein: CCR10 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membranes
Target Protein: CCR10 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine receptor Target Protein Species: Mouse Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: CCR10 Target Family: Chemokine Receptor Target Protein Species: Mouse Host Cell Type: CHO-K1-Gqi5 Assay Types: Calcium Flux Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR1 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: MKN28;CHO-K1;HEK293 Assay Types: Biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CCR10 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: MDA-MB-231;CHO-K1;HEK293 Assay Types: Biological assays
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