CCR1
The beta chemokine receptor protein that this gene produces is projected to be a seven transmembrane protein, much like G protein-coupled receptors. The ligands for this receptor are monocyte chemoattractant protein 3 (MCP-3), RANTES, regulated on activation normal T expressed and secreted protein (MIP-1 alpha), and myeloid progenitor inhibitory factor-1 (MPIF-1). The signaling pathway regulated by chemokines and their receptors is essential for attracting effector immune cells to the site of inflammation. CCR5 Pathway in Macrophages and Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions are two of its associated pathways. This gene's Gene Ontology (GO) annotations include chemokine receptor activity and G protein-coupled receptor activity.
Full Name | C-C motif chemokine receptor 1 |
Gene ID | Human: 1230 Mouse: 12768 Rat: 57301 Monkey: 574188 |
UniProt ID | Human: P32246 Mouse: P51675 Rat: Q9JLY8 Monkey: P56482 |
Alternative Names | CKR1; CD191; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1; C-C CKR-1; CC-CKR-1; CCR-1; LD78 receptor; MIP-1alpha-R; RANTES receptor; RANTES-R; chemokine (C-C motif) receptor 1; macrophage inflammatory protein 1-alpha receptor; CCR1; C-C motif chemokine receptor 1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR1 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR1 Target Family: Chemokine receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR1 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR10 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR1 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: MKN28;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR10 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: MDA-MB-231;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR10 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR10 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay