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    mProX™ Human CCR10 Stable Cell Line

    [CAT#: S01YF-0923-PY34]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX289 Magic™ Mouse CCR10 in Vitro Calcium Flux Assay Mouse CHO-K1-Gqi5 Calcium Flux Assay

    Product Information

    Target Protein
    CCR10
    Target Family
    Chemokine Family
    Target Protein Species
    Human
    Host Cell Type
    MDA-MB-231;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Immunology Research
    Related Diseases
    Mycosis Fungoides;Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
    Gene ID
    Human: 1238
    UniProt ID
    Human: O00590

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CCR10, also known as the C-C chemokine receptor type 10, is a protein that has been extensively studied in the realm of scientific research. This receptor is known to interact with specific ligands, such as CCL27 and CCL28, which play pivotal roles in various physiological processes. One of the significant findings related to CCR10 is its upregulated expression in human non-small-cell lung cancer (NSCLC) tissues and cell lines. This upregulation has been linked to the metastasis-relevant factors VEGF-C/D, MMP-2/9, and TIMP-1/2, suggesting a potential role of CCR10 in cancer progression. Furthermore, the CCR10/CCL27-CCL28 axis has been identified as dysregulated in tumor tissues, indicating its potential involvement in tumor development. Given these findings, CCR10 emerges as a potential therapeutic target in cancer research, particularly in understanding tumor progression and developing targeted interventions.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human CCR10 Stable Cell Line (S01YF-0923-PY34). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Laura (Verified Customer)

    What is the role of CCR10 in cellular processes? Mar 27 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CCR10 is another chemokine receptor with a role in immune cell signaling. It is involved in the migration and activation of specific immune cells. Mar 27 2022

    chat Michelle (Verified Customer)

    Are there any known interactions of CCR10 with other proteins or molecules? Nov 25 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CCR10 interacts with various ligands and can be part of larger signaling pathways. The specifics of these interactions are subject to ongoing research. Nov 25 2020

    Related Products by Target
    • Magic™ Human CCR10 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay (CAT#: S01YF-1222-KX350)
    • Magic™ Human FLAG tagged CCR10 CHO-K1 Gαqi5 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX266)
    • Magic™ Human FLAG tagged CCR10 HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX265)
    • mProX™ Human CCR10 Stable Cell Line (CAT#: S01YF-0923-PY34)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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