ADRB2
ADRB2 receptor is a member of the G protein-coupled receptor superfamily. The class C L-type calcium channel Ca(V)1.2, one of its ultimate effectors, is closely connected to this receptor. A G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase PP2A are also present in this receptor-channel complex. This G protein-coupled receptor has a mechanism that ensures quick and precise signaling through the construction of the signaling complex. Both the alpha-synuclein gene and this receptor's transcriptional regulator are thought to be linked to an increased risk of Parkinson's disease. This gene lacks an intron. Obesity, type 2 diabetes, cardiovascular disease, nocturnal asthma, and other polymorphic forms, point mutations, and/or downregulation of this gene are all linked to these conditions.
| Full Name | Adrenoceptor beta 2 |
| Gene ID | Human: 154 Mouse: 11555 Rat: 24176 Monkey: 710146 |
| UniProt ID | Human: P07550 Mouse: P18762 Rat: P10608 Monkey: Q28509 |
| Alternative Names | BAR; B2AR; ADRBR; ADRB2R; BETA2AR; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2 surface; beta-2 adrenoceptor; beta-2 adrenoreceptor; catecholamine receptor; ADRB2; Adrenoceptor beta 2 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB2 Target Family: Adrenergic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K2 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB2 Target Family: Adrenergic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB2 Target Family: Adrenergic Family Target Protein Species: Human Host Cell Type: HGC-27;MGC-803;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB2 Target Family: Adrenoceptor Receptors Target Protein Species: Human
- Product Category:
- Membrane Protein Tools
- Target Protein: ADRB2 Target Family: Adrenergic Family
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB2 Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB2 Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
