ADORA1
The protein encoded by ADORA1 is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. A1 receptors may also play a role in renal function and ethanol intoxication, according to animal research. A1 receptors are found on neurons throughout the CNS, including the cortex, hippocampus, and cerebellum. Astrocytes, oligodendrocytes, and microglia all have these receptors. A1 receptors are found in synaptic areas of neurons, where they control the release of neurotransmitters such glutamate, acetylcholine, serotonin, and GABA.
Full Name | Adenosine A1 receptor |
Gene ID | Human: 134 Mouse: 11539 Rat: 29290 Monkey: 703638 |
UniProt ID | Human: P30542 Mouse: Q60612 Rat: P25099 Monkey: F7E1N0 |
Alternative Names | RDC7; adenosine A1 receptor variant 1; adenosine A1 receptor variant 2; AA1R; ADORA1; Adenosine A1 receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Tools
- Target Protein: ADORA1 Target Family: Adenosine Family
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Receptors Target Protein Species: Human
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADORA1 Target Family: Adenosine Family Target Protein Species: Human Host Cell Type: A375;SK-MEL-28;CHO-K1;HEK293