mProX™ Human XCR1 Stable Cell Line

[CAT#: S01YF-0923-PY53]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Bulk Quote

Product Information

Target Protein

XCR1

Target Family

Chemokine Family

Target Protein Species

Human

Host Cell Type

Huh-7;HCCLM3;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Immunology Research;CNS Research

Related Diseases

Covid-19;Amyotrophic Lateral Sclerosis 1

Gene ID

Human: 2829

UniProt ID

Human: P46094

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Protocols

Please visit our protocols page.

Customer Reviews

There are currently no Customer reviews or questions for mProX™ Human XCR1 Stable Cell Line (S01YF-0923-PY53). Click the button above to contact us or submit your feedback about this product.

FAQ

chat Dorothy (Verified Customer)

What is the significance of XCR1 in tumor immunity? Jan 13 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

XCR1 plays a pivotal role in enhancing antitumor immunity. For instance, blocking TIM-3, an immune checkpoint, increases the exposure of intratumoral CD8+ T cells to cytokines derived from cDC1, a type of dendritic cell associated with XCR1. This has implications for designing therapeutic strategies using antibodies against TIM-3. Jan 13 2021

chat Sharon (Verified Customer)

How does XCR1 influence liver pathology in non-alcoholic steatohepatitis (NASH)? Feb 09 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

XCR1+ type 1 conventional dendritic cells (cDC1) have been identified as significant drivers of liver pathology in NASH. Comprehensive characterization of cDC biology in NASH has linked the worsening of the disease to XCR1+ cDC1. Feb 09 2022

Related Products by Target

Online Inquiry

Thank you for your interest in mProX™ Human XCR1 Stable Cell Line. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):

Estimated delivery time for your area;
Product sample or exclusive offer;
In-lab demonstration;

Creative Biolabs does not share your email address with third parties. Creative Biolabs will use your email address to confirm your identity and send you transaction-related emails, promotional and customer service emails in accordance with our privacy policy. You can change your email preferences at any time.