mProX™ Human TRPV6 Stable Cell Line
[CAT#: S01YF-1123-KX52]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Ion Channel Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The epithelial Ca2+ channel known as Transient Receptor Potential Vanilloid subfamily member 6 (TRPV6) is a member of the transient receptor potential (TRP) protein family. TRPV5 and TRPV6 are different from the other four TRPV channels (TRPV1-TRPV4) due to their high Ca2+-selectivity. While TRPV1 through TRPV3 are heat sensors with varying temperature thresholds for activation and TRPV4 is involved in osmolarity sensing, TRPV5 and TRPV6 are involved in Ca2+ transport. Early-onset chronic pancreatitis and transitory newborn hyperparathyroidism are associated with genetic abnormalities in the TRPV6 gene. In addition, skeletal abnormalities, osteoarthritis, Pendred syndrome, male infertility, hypercalciuria, kidney stone production, bone diseases, and some subtypes of cancer are associated with dysregulation of TRPV6. The customized TRPV6 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Elizabeth
Very easy to use for drug screening assay.
Oct 31 2022
Verified Customer
Anthony
Excellent service! Very reliable.
Jun 28 2020
Verified Customer
FAQ
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