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  • mProX™ Human TRPV4 Stable Cell Line

    [CAT#: S01YF-1123-KX51]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    TRPV4
    Target Family
    TRPV
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    CNS Research; Cardiovascular Research
    Related Diseases
    Spondylometaphyseal Dysplasia; Scapuloperoneal Spinal Muscular Atrophy
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The TRPV4 gene in humans encodes the ion channel protein known as transient receptor potential cation channel subfamily V member 4. The encoded protein is a nonselective, Ca2+-permeable cation channel that has been linked to a number of physiological dysfunctions, disorders, and diseases. It has a variety of roles, including the brain's control over systemic osmotic pressure, vascular, liver, intestinal, renal, and bladder functions, skin barrier and UVB radiation response, skeletal growth and structural integrity, joint function, airway and lung function, retinal and inner ear function, and pain. Chemical, mechanical, and osmotic stimuli all work to open the channel. It reacts to temperature variations as well. The customized TRPV4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Paul

    This cell line is very suitable for studying the TRPV4 signaling pathway. Mar 27 2021

    chat Verified Customer

    chat Jessica

    The TRPV4 cell line is suitable for our drug screening. Feb 21 2022

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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