mProX™ Human TRPV3 Stable Cell Line

[CAT#: S01YF-1123-KX50]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Ion Channel Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

TRPV3

Target Family

TRPV

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Ion Channel Cell Lines

Target Research Area

CNS Research; Cardiovascular Research

Related Diseases

Palmoplantar Keratoderma; Nonepidermolytic; Olmsted Syndrome

Gene ID

162514

UniProt ID

Q8NET8

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The protein of the Transient Receptor Potential Cation Channel, Subfamily V, Member 3 is encoded by the human gene TRPV3. Widespread tissue expression of the TRPV3 channel is particularly high in the skin and brain. It serves as a molecular temperature sensor in safe, heated environments. Mice that lack these proteins can feel cold and uncomfortable heat, but not high temperatures. TRPV3 channels appear to be involved in hair growth in addition to thermosensation because mutations in the TRPV3 gene cause hair loss in mice. Though its exact function in the brain is unknown, TRPV3 channels seem to be involved in mood regulation. TRPV3 acted as a partial mediator of the natural substance incensole acetate's protective properties. The customized TRPV3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Gary

Construct works beautifully, definitely will get more if needed. Apr 22 2020

chat Verified Customer

chat David

I customized a TRPV3 cell line and it's very good. Sep 06 2023

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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