mProX™ Human TACR1 Stable Cell Line

[CAT#: S01YF-0923-KX50]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types
S01YF-1122-KX649	Magic™ Mouse TACR1 in Vitro Calcium Flux Assay	Mouse	CHO-K1	Calcium Flux Assay
S01YF-1122-KX650	Magic™ Rhesus monkey TACR1 in Vitro Calcium Flux Assay	Rhesus monkey	CHO-K1	Calcium Flux Assay
S01YF-1122-KX651	Magic™ Rat TACR1 in Vitro Calcium Flux Assay	Rat	CHO-K1	Calcium Flux Assay

Product Information

Target Protein

TACR1

Target Family

Tachykinin Family

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research; Inflammation Research; Pain and Addiction Research

Related Diseases

Cystitis; Causalgia

Gene ID

6869

UniProt ID

P25103

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The TACR1 receptor is present in neurons, thyroid glands, gastrointestinal tracts, and other immune cells. It binds to the SP preferentially, indicating that it is crucial for numerous processes, including the transmission of pain and stress signals, the contraction of smooth muscles, and inflammation. Additionally, research on the TACR1 receptor has been done on bipolar disease, ADHD, alcoholism, and opioid addiction. Additionally, it has been demonstrated that several diseases, including gastrointestinal disorders, rheumatoid arthritis, and asthma, are linked to the TACR1 receptor (NK-1 receptor). A number of pathophysiological models of anxiety and depression have been treated with TACR1 receptor antagonists. The customized TACR1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Eunice

Excellent service! Very reliable. Dec 21 2022

chat Verified Customer

chat Gene

The delivery is much faster than I expected. Mar 13 2023

chat Verified Customer

FAQ

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