mProX™ Human TAAR5 Stable Cell Line

[CAT#: S01YF-0923-KX64]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

TAAR5

Target Family

Trace Amine Family

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Cancer Research; CNS Research; Orphan Receptor Research

Related Diseases

Pancreatic Somatostatinoma; Trimethylaminuria

Gene ID

9038

UniProt ID

O14804

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The TAAR5 gene in humans encodes the 38 KD protein known as the trace amine-associated receptor 5. Because recombinantly generated ''olfactory TAARs'' respond to volatile amines, including N-methylpiperidine (mTAAR7f), trimethylamine (TMA) (mTAAR5), and isoamylamine (mTAAR3), TAARs have been identified as olfactory receptors (ORs) in vertebrates. A functional trace amine-associated receptor called human TAAR5 (hTAAR5) serves as an olfactory receptor for tertiary amines. The complete agonists of hTAAR5 are trimethylamine and N, N-dimethylethylamine, while the inverse agonist of hTAAR5 is 3-iodothyronamine. Additionally, TAAR5 is nearly exclusively expressed in skeletal muscle and a few particular brain regions, including the amygdala, hippocampus, caudate nucleus, thalamus, and hypothalamus. TAAR5 is expressed in the olfactory epithelium of vertebrates. The customized TAAR5 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Bess

The prices are unbeatable, and the selection is great. Jan 19 2023

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chat James

The Human TAAR5 Stable Cell Line is so great! Apr 05 2023

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FAQ

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