mProX™ Human SSTR2 Stable Cell Line
[CAT#: S01YF-0923-KX44]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
SSTR2
Target Family
Somatostatin Family
Target Protein Species
Human
Host Cell Type
HeLa; INS-1; GH3; CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cancer Research; CNS Research
Related Diseases
Type C Thymoma; Neuroendocrine Tumor
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Somatostatin (SST) is a cyclic hormone release-inhibiting peptide that has two physiologically similar subforms, SST14 and SST28, and which negatively regulates cell proliferation, the release of numerous hormones, and the suppression of cancer by activating five SST receptors (SSTR1-5) that are specific to it. SSTR2 is primarily responsible for suppressing glucagon secretion. To selectively inhibit the release of particular hormones through various SSTR subtypes with strong receptor subtype selectivity and stability, a number of synthetic SST analogues must be developed. SSTR2 is one of the five SSTRs and exhibits abnormal expression in numerous cancer cells as well as tumor blood vessels. It inhibits cancer progression and promotes cell death. As a result, SSTR2 is a crucial pharmacological target for the treatment of numerous disorders, including cancer, thyrotropinoma, and neuroendocrine tumors (NETs). The customized SSTR2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Diana
The quality of work, efficiency, and speed was perfect.
Nov 16 2022
Verified Customer
Ahern
I customized a SSTR2 cell line and the products definitely stand out.
Mar 01 2023
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
