mProX™ Human SLCO1B3 Stable Cell Line

[CAT#: S01YF-1123-KX125]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Transporter Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-0922-KX1564	Magic™ Human SLCO1B3 in Vitro Drug screening assay	Human	Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines	Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )

Product Information

Target Protein

SLCO1B3

Target Family

SLC Transporter

Target Protein Species

Human

Host Cell Type

MCF-10A; CHO-K1; HEK293

Target Classification

Transporter Cell Lines

Target Research Area

Digestive and Renal Research; Metabolic Research

Related Diseases

Hyperbilirubinemia; Dubin-Johnson Syndrome

Gene ID

28234

UniProt ID

Q9NPD5

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The protein known as organic anion transporting polypeptide 1B3, or OATP1B3, is made by the SLCO1B3 gene. This protein is present in the cells of the liver; it carries substances from the blood into the liver where they are eliminated from the body. Bilirubin is broken down in the digestive juice known as bile in the liver and then eliminated from the body. In addition, the OATP1B3 protein carries several hormones, poisons, and medications into the liver where they are eliminated from the body. Medications for heart disease, some antibiotics, some anti-cancer treatments, and statins, which are used to treat excessive cholesterol, are among the medications carried by the OATP1B3 protein. The customized SLCO1B3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Shirley

I have used the human SLCO1B3 cell line extensively in my studies, and it consistently delivered outstanding performance. Jul 07 2021

chat Verified Customer

chat Christopher

The performance of the SLCO1B3 overexpression cell line was consistent, and the company's support team was responsive and helpful throughout the process. Jul 21 2020

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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