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SLCO1B3

This gene encodes a member of the organic anion transporter family that is exclusive to the liver. The encoded protein is a transmembrane receptor that is essential for the transport of bile acids and bilirubin and mediates the sodium-independent absorption of endogenous and xenobiotic substances. Rotor type hyperbilirubinemia is brought on by mutations in this gene.

Full Name Solute carrier organic anion transporter family member 1B3
Gene ID Human: 28234
Monkey: 574354
UniProt ID Human: Q9NPD5
Monkey: L7TAY6
Alternative Names LST3; HBLRR; LST-2; OATP8; OATP-8; OATP1B3; SLC21A8; LST-3TM13; solute carrier organic anion transporter family member 1B3; liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; organic anion transporter 8; organic anion transporter LST-3c; organic anion-transporting polypeptide 8; solute carrier family 21 (organic anion transporter), member 8; SLCO1B3; Solute carrier organic anion transporter family member 1B3

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Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: SLCO1B3 Target Family: SLC Transporter Target Protein Species: Human Host Cell Type: Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines Assay Types: Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: SLCO1B3 Target Family: SLC Transporter Target Protein Species: Human Host Cell Type: MCF-10A; CHO-K1; HEK293
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