mProX™ Human SLCO1B1 Stable Cell Line

[CAT#: S01YF-1123-KX124]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Transporter Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-0922-KX1563	Magic™ Human SLCO1B1 in Vitro Drug screening assay	Human	Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines	Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )

Product Information

Target Protein

SLCO1B1

Target Family

SLC Transporter

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Transporter Cell Lines

Target Research Area

Digestive and Renal Research; Metabolic Research

Related Diseases

Hyperbilirubinemia; Gilbert Syndrome

Gene ID

10599

UniProt ID

Q9Y6L6

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The protein known as organic anion transporting polypeptide 1B1 is made by the SLCO1B1 gene. This protein is present in the cells of the liver; it carries substances from the blood into the liver where they are eliminated from the body.The yellowish material known as bilirubin, which is created during the breakdown of red blood cells, is transported by the protein. Bilirubin is broken down in the digestive juice known as bile in the liver and then eliminated from the body. In addition, the OATP1B1 protein carries several hormones, poisons, and medications into the liver where they are eliminated from the body. OATP1B1 protein-transported pharmaceuticals include heart disease medications, some antibiotics, some cancer treatments, and statins, which are used to treat high cholesterol. The customized SLCO1B1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat John

We are delighted with the versatility and efficiency of SLCO1B1 cell line as a research tool. Jan 22 2021

chat Verified Customer

chat Lisa

Its reliability and user-friendly design have simplified the process of SLCO1B1 drug discovery in our lab. Oct 17 2020

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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