mProX™ Human SLC6A4 Stable Cell Line

[CAT#: S01YF-1123-KX135]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Transporter Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX208	Magic™ Human SLC6A4 in Vitro Radioligand Binding Assay	Human	HEK293	Radioligand Binding Assay

Product Information

Target Protein

SLC6A4

Target Family

SLC Transporter

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Transporter Cell Lines

Target Research Area

CNS Research

Related Diseases

Obsessive-Compulsive Disorder; Anxiety

Gene ID

6532

UniProt ID

P31645

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The SLC6A4 gene in humans encodes the serotonin transporter, sometimes referred to as the sodium-dependent serotonin transporter and solute carrier family 6 member 4. Serotonin reuptake is the process by which the monoamine transporter protein SERT returns the neurotransmitter serotonin from the synaptic cleft to the presynaptic cell. Serotonin is transported by the SERT protein, which then recycles it in a way that is dependent on sodium to stop its effects. In order to decrease serotonin reuptake, many antidepressant drugs from the SSRI and tricyclic antidepressant families bind to SERT. The customized SLC6A4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Timothy

As a researcher in vascular biology, I can confidently say that the SLC6A4 cell line is a fantastic tool. Oct 26 2021

chat Verified Customer

chat Helen

This SLC6A4 cell line is the best choice for laboratories wishing to minimise troubleshooting time and maximise data and experimental volumes. Sep 13 2022

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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