SLC6A4
The serotonin neurotransmitter is transported into presynaptic neurons by this gene, which encodes a crucial membrane protein. Serotonin's action is stopped and recycled by the encoded protein in a sodium-dependent way. This protein is a member of the sodium:neurotransmitter symporter family and is a target of psychomotor stimulants like cocaine and amphetamines. The rate of serotonin uptake has been demonstrated to be influenced by a repeat length polymorphism in the promoter of this gene.
| Full Name | Solute carrier family 6 member 4 |
| Gene ID | Human: 6532 Mouse: 15567 Rat: 25553 Monkey: 574140 |
| UniProt ID | Human: P31645 Mouse: Q60857 Rat: P31652 Monkey: Q9MYX0 |
| Alternative Names | HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR; sodium-dependent serotonin transporter; 5-hydroxytryptamine (serotonin) transporter; 5HT transporter; Na+/Cl- dependent serotonin transporter; serotonin transporter 1; solute carrier family 6 (neurotransmitter transporter), member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
Product List
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Magic™ Human SLC6A4 Radioligand Binding Assay
[CAT#: S01YF-1122-KX208]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: SLC6A4 Target Family: SLC Transporter Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Radioligand Binding Assay
mProX™ Human SLC6A4 Stable Cell Line
[CAT#: S01YF-1123-KX135]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: SLC6A4 Target Family: SLC Transporter Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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