mProX™ Human SLC6A2 Stable Cell Line
[CAT#: S01YF-1123-KX134]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Transporter Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
SLC6A2
Target Family
SLC Transporter
Target Protein Species
Human
Host Cell Type
SK-N-BE(2)C; SK-N-BE(2)N; CHO-K1; HEK293
Target Classification
Transporter Cell Lines
Target Research Area
CNS Research
Related Diseases
Disease; Nuclear receptors meta-pathway
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The SLC6A2 gene in humans encodes a protein called the norepinephrine transporter (NET), also referred to as the noradrenaline transporter (NAT). The sodium-chloride (Na+/Cl−)-dependent reuptake of extracellular norepinephrine (NE), also referred to as noradrenaline, is carried out by the monoamine transporter NET. Furthermore, extracellular dopamine (DA) can be reabsorbed by NET. The regulation of concentrations in the synaptic cleft is contingent upon the reuptake of these two neurotransmitters. Many antidepressants and recreational drugs target NETs and the other monoamine transporters. Additionally, ADHD is linked to an excess of NET. Evidence points to the NET gene (SLC6A2) single-nucleotide polymorphisms as a potential underlying cause of some of these illnesses. The customized SLC6A2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Jessica
The SLC6A2 cell line has exceeded my expectations in terms of performance and has become an invaluable asset in our lab.
Jul 14 2020
Verified Customer
Carol
The SLC6A2 cell line has become a crucial tool in our lab, helping us gain deeper insights into angiogenesis and related processes.
Jun 17 2022
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
