mProX™ Human SLC22A1 Stable Cell Line

[CAT#: S01YF-1123-KX128]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Transporter Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-0922-KX1567	Magic™ Human SLC22A1 in Vitro Drug screening assay	Human	Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines	Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )

Product Information

Target Protein

SLC22A1

Target Family

SLC Transporter

Target Protein Species

Human

Host Cell Type

HepG2; Hep3b; Huh6; Huh7; CHO-K1; HEK293

Target Classification

Transporter Cell Lines

Target Research Area

Cancer Research; Metabolic Research

Related Diseases

Leukemia

Gene ID

6580

UniProt ID

O15245

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The human gene SLC22A1 encodes a protein known as solute carrier family 22 member 1. Numerous endogenous small organic cations, as well as a broad range of medications and environmental pollutants, must be eliminated by the action of polyspecific organic cation transporters found in the liver, kidney, intestine, and other organs. On chromosome 6, this gene is part of a cluster including three other related cation transporter genes. The encoded protein is a plasma integral membrane protein with twelve putative transmembrane domains. For this gene, two transcript variants have been identified that yield two distinct isoforms; only the longer variation encodes a functioning transporter. It is also necessary for cells to absorb metformin. The customized SLC22A1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Lisa

The technical support team was knowledgeable and provided prompt assistance. I am extremely satisfied with this SLC22A1 cell line and the overall experience. Aug 15 2021

chat Verified Customer

chat Michael

The human SLC22A1 overexpression cell line is easy to work with and consistently provides reliable results. Jul 10 2021

chat Verified Customer

FAQ

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