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SLC22A1

Many endogenous tiny organic cations as well as a variety of medications and environmental contaminants must be eliminated, and this is made possible by polyspecific organic cation transporters found in the liver, kidney, intestine, and other organs. On chromosome 6, a cluster of three related cation transporter genes, including this one, can be found. The encoded protein is a plasma integral membrane protein with twelve putative transmembrane domains.

Full Name Solute carrier family 22 member 1
Gene ID Human: 6580
Mouse: 20517
Rat: 24904
Monkey: 703449
UniProt ID Human: O15245
Mouse: O08966
Rat: Q63089
Monkey: F7AJN0
Alternative Names OCT1; HOCT1; oct1_cds; solute carrier family 22 member 1; organic cation transporter 1; solute carrier family 22 (organic cation transporter), member 1; SLC22A1; Solute carrier family 22 member 1

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Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: SLC22A1 Target Family: SLC Transporter Target Protein Species: Human Host Cell Type: Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines Assay Types: Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: SLC22A1 Target Family: SLC Transporter Target Protein Species: Human Host Cell Type: HepG2; Hep3b; Huh6; Huh7; CHO-K1; HEK293
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