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    Family stable cell lines Voltage Gated Sodium Channel Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human SCN3A Stable Cell Line

    [CAT#: S01YF-1123-KX3]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Product Information

    Target Protein
    SCN3A
    Target Family
    Voltage Gated Sodium Channel
    Target Protein Species
    Human
    Host Cell Type
    Neuro-2a; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    Cardiovascular Research; CNS Research
    Related Diseases
    Developmental And Epileptic Encephalopathy; Epilepsy
    Gene ID
    6328
    UniProt ID
    Q9NY46

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Nav1.3 channels, which are widely distributed in the brain, are increased and discovered in dorsal root ganglion (DRG) sensory neurons after axotomy and other types of peripheral nerve injury. The significance of Nav1.3 channels in neuropathic pain is still up for debate, and their role in inflammatory pain has not yet been determined. The expression of Nav1.3 sodium channels in tiny neurons of the lumbar DRG was elevated by acute inflammation brought on by carrageenan injection into the hind paw, while Nav1.7 and Nav1.8 sodium channels were not affected in the same way. Nav1.3 mRNA is highly expressed in DRG in embryonic (E17) but significantly less so in adult rats. The customized SCN3A stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human SCN3A Stable Cell Line (S01YF-1123-KX3). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Kevin (Verified Customer)

    How is SCN3A in stable cell lines? Jan 31 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    SCN3A plays a role in various cellular processes. Ensuring its stability in cell lines is essential for accurate research outcomes. Jan 31 2022

    chat Charles (Verified Customer)

    What are the challenges associated with using SCN3A stable cell lines? Jun 18 2021

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Like other stabilized cell lines, ensuring the accurate stabilization of SCN3A is crucial. Any inconsistencies can impact the reliability of research findings. Jun 18 2021

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    • mProX™ Human SCN3A Stable Cell Line (CAT#: S01YF-1123-KX3)
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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