mProX™ Human PTGER4 Stable Cell Line
[CAT#: S01YF-0923-KX9]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
PTGER4
Target Family
Prostanoid Family
Target Protein Species
Human
Host Cell Type
Ishikawa; CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cancer Research; Reproductive Research
Related Diseases
Basosquamous Carcinoma; Malignant Epithelial Mesothelioma
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Four distinct prostanoid E receptors (EP), referred to as PTGER1-4 (also known as EP1-4), which each have seven transmembrane-spanning domains, mediate the biological effects of PGE2. These receptors are coupled to a variety of intracellular signal transduction pathways, including those that cause cAMP increases (PTGER2 and PTGER4), decreases in cAMP (PTGER3), and Ca2+ mobilization (PTGER1). PTGER4 is the most frequently expressed EP subtype among the PTGERs, and it has been shown to have functional responses in B- and T-lymphocytes, eosinophils, monocytes, and macrophages. PGE2 has been linked to the activation of PTGER4 in a number of biological activities, including the control of immunological responses and cytokine synthesis. The customized PTGER4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Madison
I customized a PTGER4 cell line and the products definitely stand out.
Jul 04 2023
Verified Customer
John
Creative biolabs can offer a good customized service.
Apr 06 2023
Verified Customer
FAQ
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