PTGER4
This gene encodes a protein that belongs to the family of G-protein coupled receptors. There are four known prostaglandin E2 receptors, and this protein is one of them. This receptor can initiate the signaling of T-cell factor. It has been demonstrated to mediate PGE2-induced early growth response 1 expression, regulate the amount and stability of cyclooxygenase-2 mRNA, and trigger the phosphorylation of glycogen synthase kinase-3. Studies using mice with this receptor's knockout suggest that it may have a role in the development of the newborn circulatory system, osteoporosis, and the start of cutaneous immunological responses.
| Full Name | Prostaglandin E receptor 4 |
| Gene ID | Human: 5734 Mouse: 19219 Rat: 84023 Monkey: 695220 |
| UniProt ID | Human: P35408 Mouse: P32240 Rat: P43114 Monkey: F7FTJ8 |
| Alternative Names | EP4; EP4R; prostaglandin E2 receptor EP4 subtype; PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype; prostaglandin E receptor 4 (subtype EP4); prostanoid EP4 receptor; PTGER4; Prostaglandin E receptor 4 |
Product List
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Magic™ Human PTGER4 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX115]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTGER4 Target Family: Prostanoid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human PTGER4 HEK293 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX275]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTGER4 Target Family: Prostanoid receptor Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Binding and Functional Assay
Magic™ Human PTGER4 HEK293 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX274]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTGER4 Target Family: Prostanoid receptor Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Calcium flux assay
Magic™ Human FLAG tagged PTGER4 HEK293T Cell Line, cAMP assay
[CAT#: S01YF-1022-KX552]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTGER4 Target Family: Prostanoid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Magic™ Cyno PTGER4 HEK293T Cell Line
[CAT#: S01YF-0123-KX279]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTGER4 Target Family: Prostanoid Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human PTGER4 Stable Cell Line
[CAT#: S01YF-0923-KX9]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTGER4 Target Family: Prostanoid Family Target Protein Species: Human Host Cell Type: Ishikawa; CHO-K1; HEK293
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