mProX™ Human PTGER1 Stable Cell Line
[CAT#: S01YF-0923-KX6]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
PTGER1
Target Family
Prostanoid Family
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cardiovascular Research; Pain and Addiction Research; Reproductive Research
Related Diseases
Tinea Barbae; Antenatal Bartter Syndrome
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The PTGER1 receptor performs a number of tasks. Hyperalgesia may be mediated by PTGER1. When given to the central nervous system, it increases pain perception, but when given systemically, it reduces pain perception. In addition to encouraging the growth of colon cancer in APC gene deletion and Azoxymethane-induced mice, it also encourages the development of hypertension in diabetic mice and spontaneously hypertensive rats. Furthermore, it might play a different role in the development of acute brain injuries. In rat models of neurological illnesses include ischemic stroke, epileptic seizures, surgically induced brain injury, and traumatic brain injury, pharmacological blockage or genetic deletion of the EP1 receptor produces positive or detrimental consequences. The customized PTGER1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Elizabeth
The PTGER1 cell line is suitable for our high-throughput drug screening.
Jul 05 2023
Verified Customer
Scarlett
Very easy to use for drug screening.
Mar 14 2023
Verified Customer
FAQ
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