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PTGER1

This gene encodes a protein that belongs to the family of G protein-coupled receptors. One of four prostaglandin E2 receptors found is this protein. The activation of this receptor is mediated by G-Q proteins via a phosphatidylinositol-calcium second messenger pathway. Studies using animals with this receptor's knockout revealed that it is involved in controlling blood pressure and mediating pain. Additionally, research on mice revealed that this gene may be responsible for the adrenocorticotropic hormone response to bacterial endotoxin.

Full Name Prostaglandin E receptor 1
Gene ID Human: 5731
Mouse: 19216
Rat: 25637
Monkey: 613251
UniProt ID Human: P34995
Mouse: P35375
Rat: P70597
Monkey: F6TQR8
Alternative Names EP1; prostaglandin E2 receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1 (subtype EP1), 42kD; prostaglandin E receptor 1 (subtype EP1), 42kDa; prostaglandin E receptor 1, subtype EP1; prostanoid EP1 receptor; PTGER1; Prostaglandin E receptor 1

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTGER1 Target Family: Prostanoid Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTGER1 Target Family: Prostanoid receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTGER1 Target Family: Prostanoid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
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