mProX™ Human PTGDR2 Stable Cell Line
[CAT#: S01YF-0923-KX4]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
PTGDR2
Target Family
Prostanoid Family
Target Protein Species
Human
Host Cell Type
HGC-27; SGC-7901; CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Inflammation Research; Digestive and Renal Research
Related Diseases
Eosinophilic Pustular Folliculitis; Asthma
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
One of the receptors for prostaglandin D2 (PGD2), which was initially discovered in type 2 helper T cells and is hence known as the chemoattractant receptor molecule expressed on Th2 (CRTH2), is prostaglandin D2 receptor 2 (PTGDR2). The majority of PGD2/PTGDR2 signaling research to date has been on the regulation of inflammatory responses and sleep promotion. Although PGD2 has long been known to have anticancer properties, there have only been a few investigations on how PGD2 affects tumor cell regulation. Researchers discovered that PGD2, produced by tumor stromal cells, prevented prostate cancer cells from proliferating. According to other studies, mast cell-derived PGD2 prevents angiogenesis in lung carcinoma and colon cancer that is linked to colitis. The function and regulatory mechanism of PGD2/PTGDR2 signaling in GC and CSCs, however, have not yet been fully uncovered by research. The customized PTGDR2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Olivia
For PTGDR2 drug discovery, this is a good choice.
Jun 18 2023
Verified Customer
Alexander
The cell line is ideal for helping to detect PTGDR2.
Aug 31 2022
Verified Customer
FAQ
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