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    mProX™ Human OPRM1 Stable Cell Line

    [CAT#: S01YF-0923-PY153]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    OPRM1
    Target Family
    Opioid Family
    Target Protein Species
    Human
    Host Cell Type
    FaDu;MDA686Tu;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Pain and Addiction Research
    Related Diseases
    Substance Dependence;Drug Dependence
    Gene ID
    Human: 4988
    UniProt ID
    Human: P35372

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The OPRM1 gene encodes the mu opioid receptor, which is the primary target of most opioid analgesics. This receptor plays a crucial role in pain perception, reward mechanisms, and addiction. Research has shown that polymorphisms in the OPRM1 gene can influence an individual's response to opioid medications, making it a significant focus in the field of pharmacogenetics. Additionally, OPRM1 has been studied for its role in various psychiatric disorders, including depression and anxiety.

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    FAQ

    chat Ashley (Verified Customer)

    Are there any known associations between OPRM1 polymorphisms and alcohol use disorder? Aug 08 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The OPRM1 gene has been studied in relation to its response to naltrexone treatment for alcohol dependence. However, some studies did not find an association of the OPRM1 Asn40Asp polymorphism with naltrexone treatment response for alcohol dependence. Aug 08 2020

    chat Gary (Verified Customer)

    How does OPRM1 gene variation influence the effects of certain treatments on heavy drinkers? May 30 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Studies have explored the therapeutic effects of targeted treatments like nalmefene on heavy drinkers in relation to polymorphic variation in opioid receptor genes, including OPRM1. However, the findings suggest that the therapeutic effects were not moderated by such polymorphic variations5. response for alcohol dependence. May 30 2022

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