OPRM1
The mu opioid receptor, one of at least three opioid receptors in humans, is encoded by this gene (MOR). Endogenous opioid peptides and opioid analgesics like beta-endorphin and enkephalins primarily target the MOR. Through its modulation of the dopamine system, the MOR also plays a significant part in reliance to other addictive substances, including nicotine, cocaine, and alcohol. The MOR has been linked to opioid and alcohol addiction as well as different levels of pain sensitivity, however there is conflicting evidence that it plays a causative role. Even though the standard MOR is a member of the superfamily of G-protein-coupled receptors with seven transmembrane domains, some of its isoforms only have six.
| Full Name | Opioid receptor mu 1 |
| Gene ID | Human: 4988 Mouse: 18390 Rat: 25601 Monkey: 574141 |
| UniProt ID | Human: P35372 Mouse: P42866 Rat: Q9MYW9 Monkey: P33535 |
| Alternative Names | MOP; MOR; LMOR; MOR1; OPRM; M-OR-1; mu-type opioid receptor; mu opiate receptor; mu opioid receptor hMOR-1a; OPRM1; Opioid receptor mu 1 |
Product List
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Magic™ Human FLAG tagged OPRM1 CHO-K1 Cell Line, β-Arrestin Assay
[CAT#: S01YF-1022-KX501]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: β-Arrestin Assay
Magic™ Human FLAG tagged OPRM1 CHO-K1 Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX500]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Assay Types: Calcium flux assay
Magic™ Human OPRM1 (NM_000914.2) CHO-K1 Gαqi5 Membrane Preparation
[CAT#: S01YF-0722-KX798]
- Product Category:
- Membranes
- Target Protein: mu Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human OPRM1 (NM_000914.2) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX799]
- Product Category:
- Membranes
- Target Protein: mu Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human OPRM1 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX745]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human OPRM1 Cell Line with 14-3-3ε Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX137]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Magic™ Human OPRM1 U2OS Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX746]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human OPRM1 Chem-5 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX937]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-5 Assay Types: Calcium flux assay
Magic™ Human OPRM1 Chem-5 Membrane Preparation
[CAT#: S01YF-0722-KX1057]
- Product Category:
- Membranes
- Target Protein: μ Target Family: Opioid Target Protein Species: Human Host Cell Type: Chem-5 Application: GTPγS Assay; Ligand Binding Assay
mProX™ Human OPRM1 Stable Cell Line
[CAT#: S01YF-0923-PY153]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Family Target Protein Species: Human Host Cell Type: FaDu;MDA686Tu;CHO-K1;HEK293 Assay Types: Biological assays
Magic™ Human OPRM1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX280]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human OPRM1 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX281]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human OPRM1 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-0822-KX748]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human OPRM1 CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX430]
- Product Category:
- Membranes
- Target Protein: Mu (OP3) Target Family: Opioid Target Protein Species: Human Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human OPRM1 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX88]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human OPRM1 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX97]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Magic™ Human OPRM1 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX117]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human OPRM1 U2OS Cell Line, Internalization assay
[CAT#: S01YF-0822-KX747]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: Internalization assay
Magic™ Mouse OPRM1 U2OS Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX669]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Mouse Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ mPro Human OPRM1 Cell Line
[CAT#: S01YF-1122-KX41]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Target Protein Species: Human
Magic™ Rat FLAG tagged OPRM1 CHO dhfr- Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX502]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Target Protein Species: Rat Host Cell Type: CHO dhfr- Assay Types: Calcium flux assay
Magic™ Rat OPRM1 ( L13069) CHO dhfr- Membrane Preparation
[CAT#: S01YF-0722-KX800]
- Product Category:
- Membranes
- Target Protein: mu Target Family: Opioid Target Protein Species: Rat Host Cell Type: CHO dhfr- Application: GTPγS Assay; Ligand Binding Assay
Magic™ Rat OPRM1 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX843]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OPRM1 Target Family: Opioid Receptors Target Protein Species: Rat Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
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