mProX™ Human OPRK1 Stable Cell Line

Product Information

Target Protein

OPRK1

Target Family

Opioid Family

Target Protein Species

Human

Host Cell Type

MDA-MB-231;MCF-7;MCF-10A;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Pain and Addiction Research

Related Diseases

Morphine Dependence;Alcohol Dependence

Gene ID

Human: 4986

UniProt ID

Human: P41145

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The OPRK1 gene encodes the kappa opioid receptor, which is primarily involved in pain perception, stress response, and mood regulation. Recent studies have shown a strong association between OPRK1 and acute pain, especially in post-surgical scenarios. Additionally, variations in the OPRK1 gene have been linked to opioid and cocaine dependence in certain populations. Understanding the role of OPRK1 in these processes can provide insights into the development of targeted therapies for pain management and addiction treatment.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Barbara (Verified Customer)

What is the significance of OPRK1 in relation to opioid and cocaine dependence? Jul 17 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

OPRK1, also known as the kappa-opioid receptor gene, has been associated with the development of cocaine and opioid dependence, especially in populations with African-American ancestry. Jul 17 2023

chat Charles (Verified Customer)

How does the OPRK1 gene polymorphism relate to heroin addiction? Jun 12 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

Polymorphisms in the OPRK1 gene, specifically the G36T polymorphism, have been found to be more frequent in individuals with heroin addiction. In a study conducted in Turkey, the G36T polymorphism and heterozygous genotype were observed to be more prevalent in the patient group with heroin use. Jun 12 2021

mProX™ Human OPRK1 Stable Cell Line

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Product Information

Product Properties

Protocols

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