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OPRK1

An opioid receptor, a member of the family of 7 transmembrane-spanning G protein-coupled receptors, is encoded by this gene. It serves as a receptor for many synthetic opioids as well as endogenous ligands. The activity of adenylate cyclase and the release of neurotransmitters are inhibited by ligand binding. This opioid receptor is involved in mediating the analgesic, hypolocomotor, and adverse effects of synthetic opioids as well as the perception of pain. Additionally linked to alcoholism and opiate addiction are variations in this gene.

Full Name Opioid receptor kappa 1
Gene ID Human: 4986
Mouse: 18387
Rat: 29335
Monkey: 710783
UniProt ID Human: P41145
Mouse: P33534
Rat: P34975
Monkey: Q95M54
Alternative Names KOP; KOR; KOR1; OPRK; KOR-1; K-OR-1; kappa-type opioid receptor; Opiate receptor, kappa-1; kappa opioid receptor; OPRK1; Opioid receptor kappa 1

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1; ARRB2 Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 β-Arrestin2 Assay Types: β-Arrestin Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Receptors Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Target Protein Species: Rat Host Cell Type: CHO dhfr- Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: OPRK1 Target Family: Opioid Family Target Protein Species: Human Host Cell Type: MDA-MB-231;MCF-7;MCF-10A;CHO-K1;HEK293
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