mProX™ Human NPFFR2 Stable Cell Line

Product Information

Target Protein

NPFFR2

Target Family

Neuropeptide FF Family

Target Protein Species

Human

Host Cell Type

Primary cytotrophoblast cell;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Metabolic Research

Related Diseases

Postsurgical Hypothyroidism;Nutmeg Liver

Gene ID

Human: 10886

UniProt ID

Human: Q9Y5X5

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Neuropeptide FF receptor 2 (NPFFR2) is a G-protein-coupled receptor that has been implicated in various physiological processes. Recent research has shed light on its potential role in the neuroendocrine regulation of reproduction. In the ricefield eel, Monopterus albus, the NPB system, which includes NPFFR2, may be involved in the neuroendocrine regulation of reproduction. Furthermore, neuropeptide B (NPB), which binds to NPFFR2, has been shown to promote differentiation of rodent white preadipocytes into mature adipocytes. This suggests that NPFFR2 may play a role in adipose tissue formation and metabolism. The ongoing research on NPFFR2 is expanding our understanding of its functions and potential therapeutic applications.

Protocols

Please visit our protocols page.

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FAQ

chat Ashley (Verified Customer)

How do primary cilia in choroid plexus epithelial cells (CPECs) modulate fluid transcytosis? Apr 09 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

Primary cilia in CPECs act as sensitive chemosensors, regulating CSF production. NPFFR2, located on these cilia, is involved in autocrine NPFF signaling, inhibiting fluid transcytosis. Deciliation elevates intracellular cAMP levels, stimulating fluid transcytosis. Apr 09 2022

chat Gary (Verified Customer)

What role does NPFFR2 play in anxiety-like behaviors in rodents? Jan 13 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

NPFFR2 activates the HPA axis, inducing anxiety-like behaviors in rodents. The direct action of hypothalamic NPFFR2 triggers these behaviors, highlighting its significance in studying anxiety and related disorders. Jan 13 2020

mProX™ Human NPFFR2 Stable Cell Line

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