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    mProX™ Human MTNR1B Stable Cell Line

    [CAT#: S01YF-0923-PY122]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    MTNR1B
    Target Family
    Melatonin Family
    Target Protein Species
    Mouse
    Host Cell Type
    MIN6;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research;Metabolic Research
    Related Diseases
    Type 2 Diabetes Mellitus;Idiopathic Scoliosis
    Gene ID
    Mouse: 244701

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Melatonin receptor 1B (MTNR1B) is the second primary receptor for melatonin. Polymorphisms in the MTNR1B gene have been associated with elevated fasting glucose levels and an increased risk of type 2 diabetes. This suggests that MTNR1B plays a role in glucose metabolism and insulin secretion. Furthermore, studies have shown interactions between MTNR1B polymorphisms and lifestyle interventions, indicating that certain genetic variants might influence the effectiveness of dietary or physical activity interventions on pregnancy outcomes. Given its influence on glucose metabolism, MTNR1B represents a potential therapeutic target for metabolic disorders, particularly type 2 diabetes.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human MTNR1B Stable Cell Line (S01YF-0923-PY122). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat James (Verified Customer)

    How does MTNR1B influence glucose tolerance and insulin secretion? May 19 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    MTNR1B is associated with glucose tolerance and insulin secretion. High endogenous melatonin levels, especially when combined with carbohydrate intake, can impair glucose tolerance, particularly in individuals carrying certain variants of the MTNR1B gene. May 19 2021

    chat Anthony (Verified Customer)

    Is there a link between MTNR1B and type 2 diabetes? Feb 20 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, certain polymorphisms in the MTNR1B gene are associated with an increased risk of type 2 diabetes. These variants can influence glucose kinetics and insulin secretion. Feb 20 2020

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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