MTNR1B
One of two high affinity receptors for melatonin, the main hormone released by the pineal gland, is encoded by this gene. This gene product is a 7-transmembrane G-protein coupled receptor that is an integral membrane protein. Although RT-PCR is required for this identification, the retina and brain are where it is primarily discovered. It is believed to have a role in the retina's light-dependent processes as well as the neurobiological effects of melatonin.
Full Name | Melatonin receptor 1B |
Gene ID | Human: 4544 Mouse: 244701 Rat: 192646 Monkey: 695629 |
UniProt ID | Human: P49286 Mouse: Q8CIQ6 Rat: P49287 Monkey: C9WT50 |
Alternative Names | MT2; FGQTL2; MEL-1B-R; melatonin receptor type 1B; mel1b receptor; melatonin receptor 1B variant b; melatonin receptor MEL1B; MTNR1B; Melatonin receptor 1B |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1B Target Family: Melatonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1B Target Family: Melatonin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1B Target Family: Melatonin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1B Target Family: Melatonin Receptors Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1B Target Family: Melatonin Target Protein Species: Mouse Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1B Target Family: Melatonin Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1B Target Family: Melatonin Family Target Protein Species: Mouse Host Cell Type: MIN6;CHO-K1;HEK293