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    mProX™ Human MLNR Stable Cell Line

    [CAT#: S01YF-0923-PY123]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    MLNR
    Target Family
    Motilin Family
    Target Protein Species
    Human
    Host Cell Type
    MRC5-SV40;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Digestive and Renal Research;Metabolic Research
    Related Diseases
    Gastroparesis;Diabetic Autonomic Neuropathy
    Gene ID
    Human: 2862
    UniProt ID
    Human: O43193

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The Motilin Receptor (MLNR) is a G-protein-coupled receptor that plays a pivotal role in gastrointestinal motility and the regulation of interdigestive migrating contractions. Research has shown that MLNR is a target for motilin, a peptide hormone, which is crucial for stimulating gastric motility. The activation of MLNR by motilin leads to increased gastrointestinal motility, which is essential for the movement of food and waste through the digestive tract. In therapeutic applications, MLNR agonists have been explored as potential treatments for gastrointestinal motility disorders, such as gastroparesis.

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    FAQ

    chat William (Verified Customer)

    What is the prognostic value of MLNR in gastric cancer patients? Apr 08 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    MLNR, or metastatic lymph node ratio, is a significant predictor for the survival of patients with gastric cancer. It can provide insights into the extent of lymph node involvement and metastasis. Apr 08 2022

    chat Jessica (Verified Customer)

    How does MLNR relate to colon cancer prognosis? Aug 10 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The combined detection of MLNR and serum CEA (carcinoembryonic antigen) can predict distant metastasis in stage II-III colon cancer patients after radical resection. Aug 10 2022

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    • Magic™ Human MLNR CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay (CAT#: S01YF-1222-KX165)
    • Magic™ Human FLAG tagged MLNR HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX456)
    • Magic™ Human MLNR CHO-K1/Gα15 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX79)
    • mProX™ Human MLNR Stable Cell Line (CAT#: S01YF-0923-PY123)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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