MLNR
The entire gastrointestinal (GI) tract expresses motilin, a 22 amino acid peptide hormone. This gene produces a motilin receptor, a protein that belongs to the G-protein coupled receptor 1 family. This family member, which is a multi-pass transmembrane protein, is a crucial therapeutic target for the treatment of illnesses involving hypomotility. A Gq/11-protein-coupled receptor that mediates progastrokinetic actions is the motilin receptor. It can be found in substantial amounts throughout the smooth muscle of the upper GI tract and at its highest concentrations in the nerves of the antral wall of the stomach.
Full Name | Motilin receptor |
Gene ID | Human: 2862 Mouse: 675957 Rat: 252859 Monkey: 705803 |
UniProt ID | Human: O43193 Mouse: A0A8B7EE64 Rat: Q9R297 Monkey: A0A5F7ZQL0 |
Alternative Names | GPR38; MTLR1; motilin receptor; G protein-coupled receptor 38; MLNR; Motilin receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin Receptors Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin Family Target Protein Species: Human Host Cell Type: MRC5-SV40;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MLNR Target Family: Motilin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay