mProX™ Human MC5R Stable Cell Line

[CAT#: S01YF-0923-PY120]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types
S01YF-1122-KX609	Magic™ Dog MC5R in Vitro cAMP Assay	Dog	CHO-K1	cAMP Assay
S01YF-1122-KX610	Magic™ Dog MC5R in Vitro Radioligand Binding Assay	Dog	CHO-K1	Radioligand Binding Assay
S01YF-1122-KX615	Magic™ Rat MC5R in Vitro cAMP Assay	Rat	CHO-K1	cAMP Assay
S01YF-1122-KX616	Magic™ Rat MC5R in Vitro Radioligand Binding Assay	Rat	CHO-K1	Radioligand Binding Assay

Product Information

Target Protein

MC5R

Target Family

Melanocortin Family

Target Protein Species

Goose

Host Cell Type

Goose Primary Hepatocytes;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research;Metabolic Research

Related Diseases

Schizophrenia 4;Familial Glucocorticoid Deficiency

Gene ID

Goose: 106034991

UniProt ID

Goose: A0A8B9DE57

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Melanocortin-5 receptor (MC5R) is another member of the melanocortin receptor family. Its expression is widespread, found in multiple tissues, including the skin, exocrine glands, and immune cells. In the context of the skin, MC5R plays a role in sebaceous gland secretion and has implications for conditions like acne. Additionally, its presence in immune cells suggests a role in modulating immune responses, though the exact mechanisms remain an active area of investigation. Given its diverse expression profile, MC5R represents a potential target for therapeutic interventions across various conditions, from dermatological to immunological disorders.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Kathleen (Verified Customer)

What is the significance of MC5R in the context of energy balance and obesity? Jan 30 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

MC5R plays a pivotal role in the regulation of energy balance and obesity. Its deficiency can lead to obesity due to increased food intake and reduced energy expenditure. Jan 30 2020

chat Sharon (Verified Customer)

How does MC5R relate to the immune response? Aug 17 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

MC5R is involved in modulating the immune response, particularly in the context of sepsis. It can influence the production of pro-inflammatory cytokines and impact the severity of sepsis. Aug 17 2020

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