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    mProX™ Human MC1R Stable Cell Line

    [CAT#: S01YF-0923-PY116]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    MC1R
    Target Family
    Melanocortin Family
    Target Protein Species
    Human
    Host Cell Type
    Primary human melanocytes (HPMs);CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Skin/Hair/Eye Pigmentation, Variation In, 2;Melanoma, Cutaneous Malignant 5
    Gene ID
    Human: 4157
    UniProt ID
    Human: Q01726

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The Melanocortin 1 Receptor (MC1R) is a G-protein coupled receptor primarily expressed in melanocytes. It plays a pivotal role in determining skin and hair color by regulating the type of melanin produced. Variants of the MC1R gene are associated with red hair, fair skin, and increased susceptibility to skin cancer. Beyond its role in pigmentation, MC1R has been implicated in anti-inflammatory responses, pain perception, and even the modulation of addictive behaviors. Its diverse functions make MC1R a subject of intense research, with implications for understanding skin biology, neurobiology, and potential therapeutic interventions.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human MC1R Stable Cell Line (S01YF-0923-PY116). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Paul (Verified Customer)

    How can MC1R genetic risk information be used in skin cancer prevention among Hispanics? Nov 10 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Precision prevention materials incorporating MC1R genetic risk information can improve skin cancer prevention activities among Hispanics, an underserved population in precision medicine. Nov 10 2022

    chat Emily (Verified Customer)

    What role does MC1R play in attenuating oxidative stress and neuronal apoptosis in neonatal hypoxic-ischemic rat models? Sep 30 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The activation of MC1R with BMS-470539 can attenuate oxidative stress and neuronal apoptosis, improving neurological deficits in neonatal hypoxic-ischemic rat models via the MC1R/cAMP/PKA/Nurr1 signaling pathway. Sep 30 2022

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    • mProX™ Human MC1R Stable Cell Line (CAT#: S01YF-0923-PY116)
    • Magic™ Human MC1R CHO-K1 Cell Line, Binding and Functional Assay (CAT#: S01YF-1222-KX307)
    • Magic™ Human FLAG tagged MC1R HEK293T Cell Line, cAMP assay (CAT#: S01YF-1022-KX430)
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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