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    mProX™ Human LPAR5 Stable Cell Line

    [CAT#: S01YF-0923-PY101]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    LPAR5
    Target Family
    Lysophospholipid Family
    Target Protein Species
    Human
    Host Cell Type
    HeLa;A549;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Gene ID
    Human: 57121
    UniProt ID
    Human: Q9H1C0

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Lysophosphatidic acid receptor 5 (LPAR5) has been spotlighted in research for its multifaceted roles in various diseases. It has been identified as a regulator of epithelial-mesenchymal transition (EMT) in cancer, influencing radioresistance in tumor cells. Moreover, its involvement in the pathogenesis of psoriasis, where it activates keratinocytes, has been documented. The therapeutic implications of LPAR5 are evident, with antagonists being explored to modulate its activity and potentially treat associated diseases.

    Protocols

    Please visit our protocols page.

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    There are currently no Customer reviews or questions for mProX™ Human LPAR5 Stable Cell Line (S01YF-0923-PY101). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Robert (Verified Customer)

    How does LPAR5 contribute to the progression of thyroid cancer? Mar 03 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    LPAR5 is involved in the progression of thyroid cancer through the TNRC6C-AS1/miR-513c-5p/LPAR5 axis, a novel signaling pathway that modulates the progression of thyroid cancer, making it a potential target for cancer therapy. Mar 03 2021

    chat Nancy (Verified Customer)

    What role does LPAR5 play in the pathogenesis of psoriasis? Jul 08 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    LPAR5 is activated by lysophosphatidic acid, mediating the pathogenesis of psoriasis by activating keratinocytes. Increased levels of LPA are associated with aggravated psoriasis-like inflammation, indicating a significant role of LPAR5 in this condition. Jul 08 2022

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    • mProX™ Human LPAR5 Stable Cell Line (CAT#: S01YF-0923-PY101)
    • Magic™ Human FLAG tagged LPAR5 RH7777 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX409)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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