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  • mProX™ Human LHCGR Stable Cell Line

    [CAT#: S01YF-0923-PY84]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    LHCGR
    Target Family
    Glycoprotein Hormone Family
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Precocious Puberty, Male-Limited;Leydig Cell Hypoplasia, Type I
    Gene ID
    Human: 3973
    UniProt ID
    Human: P22888

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Luteinizing hormone choriogonadotropin receptor (LHCGR) has been associated with various reproductive traits in livestock, such as sheep, where polymorphisms in the LHCGR gene have shown correlations with growth traits. Additionally, LHCGR has been linked to conditions like congenital idiopathic hypogonadotropic hypogonadism, emphasizing its role in reproductive health. Furthermore, studies have explored the association between LHCGR gene variants and conditions like polycystic ovary syndrome, highlighting its significance in reproductive disorders.

    Protocols

    Please visit our protocols page.

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    FAQ

    chat James (Verified Customer)

    What is the significance of Single nucleotide polymorphism (SNP) analysis in the LHCGR gene for dairy cows? Jun 24 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    SNP analysis of the LHCGR gene can be useful in improving the genetic potential of dairy cows. Specific SNPs in the LHCGR gene have been found to significantly affect the average milk yield in cross-bred cows. Jun 24 2023

    chat Ronald (Verified Customer)

    How does pregnancy influence the expression of LHCGR in pheochromocytomas? Jan 30 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Pregnancy may lead to surges in plasma catecholamine and hypertensive crises due to hCG-induced stimulation of epinephrine production by pheochromocytomas. This is influenced by the effects of estradiol and the pregnancy hormone hCG. Jan 30 2020
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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