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  • mProX™ Human KIT Stable Cell Line

    [CAT#: S01YF-1123-KX279]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    KIT
    Target Family
    Kinases/Enzyme Drug Discovery Assays and Products
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Cancer Research; Digestive and Renal Research; Reproductive Research
    Related Diseases
    Piebald Trait and Gastrointestinal Stromal Tumor. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Dasatinib-resistant KIT mutants
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The KIT gene codes for the production of a member of the receptor tyrosine kinase protein family. A process known as signal transduction is used by receptor tyrosine kinases to transfer messages from the cell surface within the cell. The KIT protein is located in the membrane of some types of cells where it binds to a particular protein known as stem cell factor. The KIT protein is activated by this interaction, and it adds a cluster of oxygen and phosphorus atoms at certain locations to other proteins within the cell to activate them as well. Phosphorylation is the process that causes several proteins in various signaling pathways to become active. The customized KIT stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Kevin

    I think this is a quality KIT overexpression cell line for drug discovery. Jul 18 2021

    chat Verified Customer

    chat Anthony

    Very good KIT cell line for drug discovery. Feb 12 2020

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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