mProX™ Human KCNN2 Stable Cell Line
[CAT#: S01YF-1123-KX39]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Ion Channel Cell Lines
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Another name for the ion channel protein KCNN2 is KCa2.2. In vertebrate neurons, action potentials are followed by an afterhyperpolarization (AHP) that can last for a few seconds and has a significant impact on the neuron's firing pattern. Different calcium-activated potassium channels mediate each of the AHP's kinetically unique components. The slow component of synaptic AHP is assumed to be regulated by the KCa2.2 protein, which is activated prior to membrane hyperpolarization. Together with three other calmodulin-binding subunits, KCa2.2, an integral membrane protein, forms a voltage-independent calcium-activated channel. This protein belongs to the family of potassium channels that are activated by calcium. For the KCNN2 gene, two transcript variants encoding distinct isoforms have been discovered. The customized KCNN2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Ronald
Cost-effective and scalable bioprocess with robust and reliable tech transfer.
Feb 22 2020
Verified Customer
Michelle
In-house state of the art tech revolutionizing our development programs.
Jul 26 2021
Verified Customer
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