KCNN2
In vertebrate neurons, action potentials are followed by an afterhyperpolarization (AHP) that may last for many seconds and may have significant effects on the neuron's firing pattern. Each AHP component has its own unique kinetics and is controlled by a unique calcium-activated potassium channel. This gene's protein contributes to the slow portion of synaptic AHP and is hypothesized to control neuronal excitability. The protein is activated prior to membrane hyperpolarization. Together with three other calmodulin-binding subunits, the encoded protein forms an integral membrane protein that functions as a voltage-independent calcium-activated channel. The potassium channel gene KCNN family includes this gene.
| Full Name | Potassium calcium-activated channel subfamily N member 2 |
| Gene ID | Human: 3781 Mouse: 140492 Rat: 54262 Monkey: 695374 |
| UniProt ID | Human: Q9H2S1 Mouse: P58390 Rat: P70604 Monkey: F6VI99 |
| Alternative Names | KCNN2; SK2; hSK2; SKCA2; KCa2.2; SKCa 2; small conductance calcium-activated potassium channel protein 2; apamin-sensitive small-conductance Ca2+-activated potassium channel; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel 2; Potassium calcium-activated channel subfamily N member 2 |
Product List
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Magic™ mPro Human KCNN2 Cell Line
[CAT#: S01YF-1122-KX90]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNN2 Target Family: Calcium and Sodium Activated Potassium Channel Target Protein Species: Human
mProX™ Human KCNN2 Stable Cell Line
[CAT#: S01YF-1123-KX39]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNN2 Target Family: SKCa Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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