mProX™ Human KCNN1 Stable Cell Line
[CAT#: S01YF-1123-KX38]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Ion Channel Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
KCNN1
Target Family
SKCa
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Ion Channel Cell Lines
Target Research Area
Cardiovascular Research; CNS Research
Related Diseases
Mental Retardation; Developmental And Epileptic Encephalopathy
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
A human gene that codes for the KCa2.1 protein is called potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1. It is sometimes referred to as KCNN1. In vertebrate neurons, action potentials are followed by an afterhyperpolarization (AHP) that can last for a few seconds and has a significant impact on the neuron's firing pattern. Different calcium-activated potassium channels mediate each of the AHP's kinetically unique components. The protein that this gene encodes is hypothesized to control neuronal excitability by contributing to the slow part of synaptic AHP. It is activated prior to membrane hyperpolarization. Together with three other calmodulin-binding subunits, the integral membrane protein KCa2.1 forms a voltage-independent calcium-activated channel. The KCNN1 gene belongs to the potassium KCNN family. The customized KCNN1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Dorothy
The Human KCNN1 Stable Cell Line is so great!
Jun 28 2022
Verified Customer
Sharon
Success assurance with the best cell line, right from the start.
Apr 04 2023
Verified Customer
FAQ
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