KCNN1

In vertebrate neurons, action potentials are followed by an afterhyperpolarization (AHP) that may last for many seconds and may have significant effects on the neuron's firing pattern. Each AHP component has its own unique kinetics and is controlled by a unique calcium-activated potassium channel. This gene's protein contributes to the slow portion of synaptic AHP and is hypothesized to control neuronal excitability. The protein is activated prior to membrane hyperpolarization. Together with three other calmodulin-binding subunits, the encoded protein forms an integral membrane protein that functions as a voltage-independent calcium-activated channel. The potassium channel gene KCNN family includes this gene.

Full Name	Potassium calcium-activated channel subfamily N member 1
Gene ID	Human: 3780 Mouse: 84036 Rat: 54261 Monkey: 720091
UniProt ID	Human: Q92952 Mouse: Q9EQR3 Rat: P70606 Monkey: H9FU72
Alternative Names	KCNN1; SK1; hSK1; SKCA1; KCa2.1; small conductance calcium-activated potassium channel protein 1; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1; small conductance calcium-activated potassium channel 1; SK; Potassium calcium-activated channel subfamily N member 1

Product List

mProX™ Human KCNN1 Stable Cell Line [CAT#: S01YF-1123-KX38]

Product Category:: Membrane Protein Stable Cell Lines

Datasheet

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