mProX™ Human KCNMA1 Stable Cell Line
[CAT#: S01YF-1123-KX37]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Ion Channel Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
KCNMA1
Target Family
BKCa
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Ion Channel Cell Lines
Target Research Area
Cardiovascular Research; CNS Research
Related Diseases
Paroxysmal Nonkinesigenic Dyskinesia; Liang-Wang Syndrome
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The KCNMA1 gene codes for the voltage-gated calcium-activated potassium channel subunit alpha-1, also referred to as the large conductance calcium-activated potassium channel, subfamily M, alpha member 1 (KCa1.1), or BK channel alpha subunit. It is distinguished by its high conductance of potassium ions (K+) across cell membranes. Alterations in the electrical potential of the membrane and/or elevations in the intracellular calcium ion concentration can activate BK channels. K+ can passively move via open BK channels and down the electrochemical gradient. This causes an efflux of K+ from the cell under normal physiological conditions, which in turn causes hyperpolarization of the cell membrane and a reduction in the excitability of the cell. The customized KCNMA1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Karen
I had a wonderful encounter with this business. Excellent KCNMA1 cell line was provided.
Jun 24 2023
Verified Customer
Sandra
The prices are unbeatable, and the selection is great. I will customize cell line again.
Jan 30 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
