KCNMA1
The potassium channel KCNMA1, which facilitates K(+) export, is triggered by both membrane depolarization and a rise in cytosolic Ca(2+). Additionally, the amount of cytosolic Mg(2+) activates it. The excitatory events that increase the cytosolic Ca(2+) content and/or depolarize the cell membrane are muted by its activation. As a result, it aids in repolarizing the membrane potential. plays a significant part in regulating transmitter release, smooth muscle contraction, cochlear hair cell tuning, and innate immunity, among other systems that are subject to excitability control. The membrane potential in smooth muscles is regulated by its activation by high Ca(2+) levels, which are brought on by ryanodine receptors in the sarcoplasmic reticulum.
| Full Name | Potassium calcium-activated channel subfamily M alpha 1 |
| Gene ID | Human: 3778 Mouse: 16531 Rat: 83731 Monkey: 574103 |
| UniProt ID | Human: Q12791 Mouse: Q08460 Rat: Q62976 Monkey: O18867 |
| Alternative Names | SLO; BKTM; SLO1; hSlo; IEG16; LIWAS; MaxiK; PNKD3; SAKCA; mSLO1; CADEDS; KCa1.1; SLO-ALPHA; bA205K10.1; calcium-activated potassium channel subunit alpha-1; uncharacterized protein LOC3778; BK channel alpha subunit; BKCA alpha subunit; big potassium channel alpha subunit; calcium-activated potassium channel, subfamily M subunit alpha-1; k(VCA)alpha; maxi-K channel HSLO; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; slo homolog; slowpoke homolog; stretch-activated Kca channel; KCNMA1; Potassium calcium-activated channel subfamily M alpha 1 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNMA1 Target Family: Calcium and Sodium Activated Potassium Channel Target Protein Species: Human
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNMA1 Target Family: BKCa Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
