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  • mProX™ Human KCNJ4 Stable Cell Line

    [CAT#: S01YF-1123-KX44]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    KCNJ4
    Target Family
    GIRK
    Target Protein Species
    Human
    Host Cell Type
    Calu-3; A549; NCI-H209; NCI-H460; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    Cardiovascular Research; CNS Research
    Related Diseases
    Andersen Cardiodysrhythmic Periodic Paralysis; Epilepsy
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    KCNJ4, sometimes referred to as Kir2.3 or potassium inwardly-rectifying channel, subfamily J, member 4, is a gene found in humans. The nervous system's electrical signaling is known to be mediated by a number of distinct potassium channels. This imbalance in the conductance of potassium ions is crucial for the excitability of neurons and muscle cells. This gene codes for an integral membrane protein that belongs to the family of potassium channels found in inward rectifiers. In comparison to other proteins in this family, the encoded protein has a low unitary conductance. For this gene, two transcript variants that encode the same protein have been discovered. The customized KCNJ4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

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    Customer Reviews

    chat Kimberly

    A great customized cell line. Nov 04 2021

    chat Verified Customer

    chat Donna

    The Human KCNJ4 Stable Cell Line worked well! Sep 12 2021

    chat Verified Customer

    FAQ

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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