KCNJ4

Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.

Full Name	Potassium inwardly rectifying channel subfamily J member 4
Gene ID	Human: 3761 Mouse: 16520 Rat: 116649 Monkey: 721015
UniProt ID	Human: P48050 Mouse: P52189 Rat: P52190 Monkey: A0A1D5RE55
Alternative Names	HIR; HRK1; IRK3; HIRK2; IRK-3; Kir2.3; inward rectifier potassium channel 4; hippocampal inward rectifier potassium channel; inward rectifier K(+) channel Kir2.3; potassium channel, inwardly rectifying subfamily J, member 4; potassium voltage-gated channel subfamily J member 4; KCNJ4; Potassium inwardly rectifying channel subfamily J member 4

Product List

mProX™ Human KCNJ4 Stable Cell Line [CAT#: S01YF-1123-KX44]

Product Category:: Membrane Protein Stable Cell Lines

Datasheet

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