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    mProX™ Human HCAR3 Stable Cell Line

    [CAT#: S01YF-0923-PY149]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    HCAR3
    Target Family
    Nicotinic Acid Family
    Target Protein Species
    Human
    Host Cell Type
    HEK293;N/TERT2G;CHO-K1
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Digestive and Renal Research;Metabolic Research
    Related Diseases
    Pellagra;Hypoalphalipoproteinemia, Primary, 1. Am
    Gene ID
    Human: 8843
    UniProt ID
    Human: P49019

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    HCAR3, known for its role in cellular metabolism and immune responses, has been identified as a potential drug target. Recent studies have highlighted its association with colorectal cancer, suggesting HCAR3 and INSL5 as potential therapeutic targets. Additionally, its involvement in tryptophan metabolism and its upregulation in inflammatory conditions like Crohn's disease further emphasize its potential therapeutic implications.

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    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human HCAR3 Stable Cell Line (S01YF-0923-PY149). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Barbara (Verified Customer)

    What is the significance of HCAR3 in neuronal activity? Nov 18 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    HCAR3 activation in neurons can modulate neuronal activity through presynaptic mechanisms and by reducing neuronal excitability, making it a key player in the regulation of neuronal network activity. Nov 18 2020

    chat Carol (Verified Customer)

    Are there any known associations between HCAR3 and programmed cell death? Jan 27 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    While HCAR3's direct role in programmed cell death is not explicitly mentioned, proteins like Bcl-2, an inner mitochondrial membrane protein, have been known to interfere with programmed cell death. Jan 27 2022

    Related Products by Target
    • Magic™ Human FLAG tagged HCAR3 CHO-K1 Cell Line, cAMP assay (CAT#: S01YF-1022-KX489)
    • mProX™ Human HCAR3 Stable Cell Line (CAT#: S01YF-0923-PY149)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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